Myeloma associated amyloidosis presenting as subacute liver failure
نویسندگان
چکیده
منابع مشابه
Multiple Myeloma Presenting as Acute Liver Failure
Liver failure is rarely caused by multiple myeloma (MM). We present an unusual case of MM initially presenting as acute liver injury. A 79-year-old man with new-onset fatigue, decreased appetite, and no history of liver disease was found to have evidence of hepatic decompensation. Liver biopsy demonstrated diffuse plasma cell infiltration, and MM was confirmed with bone marrow biopsy. Chemother...
متن کاملAmyloidosis presenting as acute liver failure: a case report
Introduction: Amyloidosis has two principle types: multiple myeloma-associated (AL) and amyloidassociated amyloidosis (AA). Both types can be local or systemic and can often involve the liver. Hepatic amyloidosis carries a poor prognosis, but commonly presents with a more gradual time course of evolving hepatomegaly and elevated serum alkaline phosphatase. This casereport involves an unusual pr...
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Amyloidosis is a generic term that refers to the deposition of amyloid fibrils in bodily tissues. Its onset is usually after 40 years of age, with localized or systemic involvement associated with multiple myeloma or chronic inflammatory diseases, and can mimic various rheumatic syndromes. We report the case of a patient with amyloidosis associated with multiple myeloma, showing clinical charac...
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Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase are the most common clinical and biochemical findings, respectively. We report a case of systemic...
متن کاملSubacute liver failure secondary to amyloid light-chain amyloidosis.
A previously healthy 50-year-old man presented to his primary care physician with fatigue. Screening blood tests revealed a bilirubin level of 14 μmol/L (0.82 mg/dL), an aspartate aminotransferase (AST) level of 57 IU/L, an alkaline phosphatase (ALP) level of 72 IU/L, a g-glutamyltranspeptidase level of 126 IU/L, an albumin level of 30 g/L, and hypercholesterolemia. Results from hepatitis B and...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 2006
ISSN: 0032-5473
DOI: 10.1136/pgmj.2006.044883